European scientists have identified the origins of your seasonal allergy. It is apparently linked to your molecular ecosystem of dust mite allergy.
A team of researchers from the Medical University of Vienna and The Charité - Universitätsmedizin Berlin found that allergic reactions to dust mites at home start from a molecular level inside the human body from a very young age, and can develop into something worse through time. This molecular development can escalate into severe health issues.
According to the author of the study, Daniela Posa of the Charité - Universitätsmedizin, seasonal allergy to dust mites develop like an avalanche as it begins early with just a very few molecules then grows into a significant ecosystem. Those with the highest risk of developing asthma also have a greater spread of molecular sensitization.
The research team engineered mite molecules known as Dermatophagoides pteronyssinus to observe the antibody response of these children within the first 10 years of their lives. By using this special method, the team found that IgE antibodies against three dust mite molecules thrived early during childhood before any diseases would develop such as seasonal allergy. Those children who continued to produce this type of molecule were more prone to developing allergic rhinitis and asthma.
In this new study, scientists sought to gain a better understanding of how allergies from dust mites begin to develop and to also find new ways to effectively predict and prevent seasonal allergy linked to dust mite allergy and asthma linked to this molecular ecosystem.
This new study was published in The Journal of Allergy and Clinical Immunology.