Scientists have discovered that naked mole rats are tough creatures due to an alternation in their nerves. Aside from pain resistance, the rats have other enviable qualities.

Naked mole rats are the bizarre subterranean creatures that live underground in the east African dessert. Previous studies have shown that these creatures are cancer-resistant and can live up to 30 years.

Now, Gary Lewin, a neuroscientist at the Max Delbrück Center for Molecular Medicine, and his team of researchers from Berlin have discovered the genetic selection of these creatures that makes them impervious to pain.

By isolating single nerve cells from the naked mole rat, Lewin and his team discovered that their molecular dock differs from that of other mole rats. Pain pathways are kicked off when a substance called the nerve growth factor is released by inflamed cells. The factor binds to a receptor called the "TrKA," which deliver pain messages to the cells.

"Even though the naked mole rat's version of the TrkA receptor is almost identical to that of a mouse or a rat, it has a very significant effect on the animal's ability to feel pain," Lewin explained.

The researchers were impressed at how a small change to a single molecule can result in a whole adaptation. The naked mole rat can inspire better pain treatments. The study proves significant because there is a possibility that one day, scientists might be able to harness these abilities in humans. In doing so, it could be used to help people who are dealing with serious illnesses including autoimmune diseases.